Sildenafil: What it is and why people use it

Sildenafil is a medicine best known as Viagra. It helps increase blood flow to certain parts of the body and is used most often for erectile dysfunction (ED). Doctors also prescribe specific doses for pulmonary arterial hypertension (PAH). It can start working in about 30–60 minutes and usually lasts 3–5 hours for ED, though people feel different effects.

How sildenafil works and dosing quick guide

Sildenafil blocks an enzyme called PDE5 so blood vessels relax and widen. For ED the usual starting dose is 50 mg taken about an hour before sex. Doctors may lower it to 25 mg or raise it to 100 mg depending on how you respond and any side effects. Take it no more than once daily.

For pulmonary hypertension (sold as Revatio in some regions) doses are smaller and typically taken three times a day—commonly 20 mg three times daily. Never mix instructions for PAH with ED dosing without your doctor’s guidance.

Safety, side effects and buying tips

Common side effects include headache, flushing, stuffy nose, indigestion, and mild vision change (a blue tint). Serious but rare risks: sudden vision loss, sudden hearing loss, priapism (painful erection lasting over 4 hours), and large drops in blood pressure if taken with nitrates. If you use nitroglycerin or other nitrates, do not take sildenafil.

Watch for drug interactions: alpha-blockers, some HIV and antifungal meds, and grapefruit juice can increase sildenafil levels and risk side effects. Tell your doctor about heart disease, low blood pressure, recent stroke, severe liver or kidney problems before using it.

Buying online: sildenafil requires a prescription in most countries. If you see low-cost pills sold without prescription, be cautious. Choose licensed online pharmacies that ask for a prescription, show a real contact address, and have secure checkout. Counterfeit pills can contain wrong doses or dangerous ingredients. Read independent reviews and check pharmacy verification sites when possible.

Some new products marketed as "female Viagra" or topical creams have turned up containing sildenafil or similar actives. These are risky if unlabelled or sold without a doctor’s oversight. If you’re curious about sexual function for women, talk to a clinician rather than trying unverified products.

Storage and when to see help: store sildenafil at room temperature away from moisture. Seek immediate medical help for sudden vision or hearing loss, chest pain, or erections lasting more than 4 hours. If you have side effects that interfere with daily life, call your doctor — dosing or an alternative may be safer for you.

Sildenafil works for many people, but it’s not right for everyone. A short talk with your healthcare provider will help you find the right dose, check drug interactions, and avoid fake online sellers. That makes the medicine both safer and more effective.

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